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' ' WE WE.RE AB LE T@~BLOCK ~ TREMELY LARGE DOSES OF FENTANYL TO PROTECT AGAINST OVERDOSES - Paul Bremer

SAFE AND POWERFUL Not only was the vaccine able to stop intoxication (something researchers suggest could aid in opioid addiction treatment), the vaccine also proved extreme ly effective in blocking the potentially lethal effects of fentanyl as well. Whi le the chemical is not necessarily toxic in itself, it does produce psychoact ive effects that can shut down breathing and stop a person's heart. Researchers say mice injected with the vaccine could withstand doses of fentanyl up to 30 t imes the

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"For unrelated drugs that you would be taking, there would be no effect from the vaccine," Bremer says. LOOKING TOWARD THE

FUTURE

normal rate.

"It was juS t a firS t generation vaccine, but it

Although still in the early stages of development, resea rchers say the vaccine represents an exciting step forwa rd in drug vaccine research. The lab is beginning more advanced trials on a similar heroin

did prove to be very

potent," Bremer says. "We were able to block extremely large doses of fentanyl to protect against overdoses."

A SINGLE PURPOSE

vaccine which should give Researchers say the vaccine them a better idea of how would not protect against successful the fentanyl heroin or oxycodone, and a vaccine could become. But mixture of vaccines would until more testing can be ----A·e Aeeeleel te f3Feteet===t<=eeFAf3leteel, FeseaFehers s"By against all opioids. But that they were pleased with the was somewhat by design. progress and excited for the To make sure the vaccine future of vaccines in the would not interfere with any treatment of addiction. medications a person may "This concept of using a take responsibly later in life, vaccine for addiction isn't researchers targeted just an academic pursuit, it specific molecules so the could really be used in vaccine would only block practice," Bremer says. "I fentanyl and its derivatives. think it's really promising."

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